STRUCTURE NOTE Structure of YciI fromHaemophilus influenzae (HI0828) Reveals a Ferredoxin-Like / -Fold with a Histidine/Aspartate Centered Catalytic Site
نویسندگان
چکیده
Mark A. Willis, Feng Song, Zhihao Zhuang, Wojciech Krajewski, Vani Rao Chalamasetty, Prasad Reddy, Andrew Howard, Debra Dunaway-Mariano, and Osnat Herzberg* Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland Department of Chemistry, University of New Mexico, Albuquerque, New Mexico The National Institute of Standards and Technology, Gaithersburg, Maryland Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois Biological, Chemical, and Physical Sciences, Illinois Institute of Technology, Chicago, Illinois
منابع مشابه
Secondary Structure Effects on the Acidity of Histidine and Lysine-Based Peptides Model; A Theoretical Study
In this study, the effect of the secondary structure of the protein on the acid strength of three structures of random (R), alpha helix (α) and beta sheet (b) were investigated theoretically. These structures are related to the cationic amino acids of histidine and lysine in the polypeptide chain of eight-glycine residue. Computational methods at the HF, B3LYP, X3LYP and M05-2X levels in t...
متن کاملSTRUCTURE NOTE Crystal structure of tflp: A ferredoxin-like metallo-b-lactamase superfamily protein from Thermoanaerobacter tengcongensis
Ferredoxins are a group of proteins containing nonheme iron and acid-labile sulfur. They are ubiquitous electron transfer proteins participating in a wide variety of redox reactions. Many organisms express multiple ferredoxins.1 Three types of [Fe-S] clusters have been described so far in ferredoxins: [2Fe-2S], [3Fe-4S], and [4Fe-4S]. The structures of these [Fe-S] clusters have substantial inh...
متن کاملA conserved histidine-aspartate pair is required for exovinyl reduction of biliverdin by a cyanobacterial phycocyanobilin:ferredoxin oxidoreductase.
Phycocyanobilin:ferredoxin oxidoreductase is a member of the ferredoxin-dependent bilin reductase family and catalyzes two vinyl reductions of biliverdin IXalpha to produce phycocyanobilin, the pigment precursor of both phytochrome and phycobiliprotein chromophores in cyanobacteria. Atypically for ferredoxin-dependent enzymes, phycocyanobilin:ferredoxin oxidoreductase mediates direct electron t...
متن کاملHomology modeling and identification of serine 160 as nucleophile of the active site in a thermostable carboxylesterase from the archaeon Archaeoglobus fulgidus.
The hyperthermophilic Archaeon Archaeoglobus fulgidus has a gene (AF1763) which encodes a thermostable carboxylesterase belonging to the hormone-sensitive lipase (HSL)-like group of the esterase/lipase family. Based on secondary structure predictions and a secondary structure-driven multiple sequence alignment with remote homologous proteins of known three-dimensional structure, we previously h...
متن کاملThermodynamics for complex of L-histidine with molybdenum (VI) Model Anticancer Drugs
Organometallic complexes offer potential for design as anticancer drugs. A quantitativemodel that discriminates anticancer compounds from the inactive ones in a training series wasEquilibrium of the reaction of molybdenum (VI) with l-histidine have been studiedin aqueous solutions at pH range of 4-8, using spectrophotometry and optical rotationmethods at constant ionic strength of 0.15 mol.lit-...
متن کامل